Testosterone is essential to the regulation of insulin, glucose, and fat storage. Managing your body’s insulin production is the key to reducing inflammation as one ages. As testosterone levels plummet, so does your body’s ability to process insulin, glucose, and fat. Simply put, a decrease in testosterone levels is directly correlated with an increase in fat storage.To make matters worse for obese men with 25% body fat or higher, an increase in fat also lowers testosterone levels. The fatter you become, the lower your testosterone levels go. This vicious cycle is a huge contributor to the obesity pandemic sweeping the world. In the United States is reporting that 4 out of 10 adults are obese.In obese males, there is increased aromatase activity which is aromatase is the enzyme directly responsible for converting testosterone into estrogen, and results in decreased testosterone levels and elevated estrogen levels. However, obese and high body fat men alike can break this cycle by undergoing Testosterone Optimization Therapy (TOT) due to testosterone being lipolytic such as fat burning. Studies have also shown that one of the positive benefits of testosterone treatment is a decrease in abdominal adiposity which is also known as fat storage.Testosterone levels are lower in men with obesity, metabolic syndrome, and type 2 diabetes. You can see this just by looking around, as obesity is increasing dramatically across most of the world. We all know the reasons behind this: poor diet, and a lack of exercise are literally killing us. Recent studies indicate that TOT in men with type 2 diabetes has beneficial effects on decreasing insulin resistance and lowering visceral body fat, both of which play a key role in cardiovascular disease.
TOT has been proven to increase lean body mass (LBM), reduce fat mass, reduce waist circumference and BMI, and produce sustained and significant weight loss. Wouldn’t TOT in obese men with low levels of testosterone be a unique and effective therapeutic approach to the management of obesity? Of course, it would. And if you’re already an obese man, a very recent study says that being testosterone deficient will dramatically increase your risk of death.Aromatase, the enzyme responsible for converting testosterone to estrogen, is more abundant in fat tissue. The higher your body fat percentage, the more aromatase enzymes you have floating around and the more likely you are to convert supplemental testosterone into estrogen (estradiol, E2). This conversion happens more often in stubborn body fat deposit areas which contain specific stubborn fat receptor cells with poor blood flow, such as the fat tissue found in the love handles, chest, and upper and lower back.In other words, the higher your body fat percentage, the more likely you are to be susceptible to negative estrogen-induced side effects like poor erectile strength, moodiness, water retention, increased fat deposition, and so on (from high estrogen levels).
For men with high body fat percentages who are starting TOT, it may be prudent to use a minimum effective dose of an AI medication after initiating testosterone therapy to minimize potential estrogen-induced side effects. This is a temporary solution, due to the potential damage to HDL and bone mineral density that the AI medications can cause. Always discuss this with your physician and make sure to regularly monitor sensitive E2 (estrogen) levels throughout therapy until balance (i.e. feeling good with no side effects) is achieved.If your body fat is above 20% and you want to ensure that you are minimizing potential aromatization and estrogenic side effects, you should prioritize losing body fat while undergoing TOT.To learn how to fully optimize your health and life, read the Amazon best selling TOT Bible.